I finally got all my isseus sorted out with connecting the CR-6SE to my WIn10 Computer and now started to print directly via SImplified 3D. I'm sure I will need to treak the profile etc as I learn more.
My problem/observation is the following:
If I have the USB cable plugged into the CR-6 and turn off the CR-6, it seems to be receiving power via the USB cable. The screen backlight seems to be visibly very faint and the Win10 Device for the CR-6 is still active. I can pull the USB plug but that will destroy the port over a short period of time. This does not seem to be a good idea.
On my CR-10 if you powered down everything powered down.