So I’ve spent days tuning and saving profiles in 5.1.7 for my K1C and E3V3. I come back to the software a few days later and they’re gone! Config and filament settings…. Gone !
Spend another day or two trying to redo them. Next time opening…… NOOOOOO! Bloody gone again. I’m seriously cheesed off with this CRPrint, bring back good ol Cura 
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It starts looking and saving stuff in a different folder if you get logged out. For example, my profile info was stored in the following location:
C:\Users<windows username>\AppData\Roaming\Creality\Creality Print\6.0\user<random number>
Next time I updated the software, my profiles disappeared. It turned out that I got logged out and it was now looking for everything here:
C:\Users<windows username>\AppData\Roaming\Creality\Creality Print\6.0\user\default
Make sure you’re still logged in, figure out where it’s looking for profile information, and move files between folders if necessary.