Best way to print this model

Hi all,

I’m just a new bi.
Guys can you tell me how to print this model on a Creality Ender 3 V3 Ke.
My problem is the round chamber i believe you can’t print in the air (see attachment)

Does the area beneath the angled face need to be open or could it be redesigned to fill that bit in? As it is I would probably print it with the largest face on the bed and use supports, probably not tree, with minimal interface. Which material?

Oke thank you its better to redesign